PRF vs. PRP: What’s Better for Skin Rejuvenation and Volume Loss?
Our Team
7/13/2025
Introduction
Regenerative aesthetics has quickly become one of the most exciting frontiers in non-surgical facial rejuvenation. If you’ve heard about PRP (Platelet-Rich Plasma) or PRF (Platelet-Rich Fibrin), you’re not alone — both treatments use your body’s own healing factors to improve skin tone, texture, and volume. But which one is better?
At Enclave Med Spa in San Elijo, we specialize in advanced regenerative therapies that go beyond surface-level treatments. In this post, we break down the science, applications, and advantages of PRF vs. PRP — and why we choose PRF for our patients seeking natural, long-term results.
What Is PRP (Platelet-Rich Plasma)?
PRP has been used for over a decade in both medicine and aesthetics. It involves drawing a small amount of your blood, spinning it in a centrifuge to isolate platelet-rich plasma, and then injecting or microneedling it into the skin.
How PRP Works:
Delivers growth factors and platelets to accelerate healing
Often used in “vampire facials” or post-microneedling
Improves overall tone, texture, and healing response
Great for boosting collagen and healing after laser or RF
However, PRP uses an anticoagulant during processing to prevent clotting. This limits how long the growth factors remain active once reintroduced into the skin — they’re released all at once, then gone.
What Is PRF (Platelet-Rich Fibrin)?
PRF is the next-generation version of PRP — and it’s what we use at Enclave Med Spa. Like PRP, PRF is derived from your blood, but it’s spun at a slower speed and does not use anticoagulants.
This slower spin preserves more:
Platelets
Leukocytes (white blood cells)
Fibrin matrix
Stem cells
And most importantly, releases growth factors slowly over time
This means PRF stays active longer in your skin, allowing continued collagen production, improved skin quality, and gentle volume enhancement.
Key Differences Between PRP and PRF
Feature PRP PRF
Anticoagulant Used Yes No
Spin Speed High Low
Growth Factor Release Immediate Sustained (10–12 days)
Volume Restoration Minimal Moderate
Texture Improvement Good Excellent
Duration of Results Weeks Months
When Should You Choose PRF?
We recommend PRF for clients who want a natural, non-toxic, long-lasting rejuvenation strategy. PRF is ideal for:
Under-eye hollows and darkness
Fine lines around the mouth or eyes
Crepey skin texture
Loss of volume in cheeks, temples, or jawline
Patients who want natural results without dermal fillers
Clients seeking enhanced microneedling outcomes
How Many Treatments Are Needed?
Most clients benefit from a series of 2–3 PRF sessions, spaced about 4–6 weeks apart. Improvements continue gradually over the following 2–3 months as collagen rebuilds.
Why Enclave Med Spa in San Elijo Recommends PRF
We use only next-generation PRF, with custom protocols for injection and microneedling. Every treatment is personalized to your anatomy and skin needs. Our providers are clinically trained in regenerative aesthetics, and we combine PRF with modalities like Morpheus8, IPL, and chemical peels for amplified results.
Unlike clinics that still offer PRP out of habit, we choose PRF because it works better — and our patients see it in the mirror.
Internal Links
Learn more about Morpheus8 treatments
Explore our Membership Plans
Book a consultation
Ready to See the PRF Difference?
Experience next-level regenerative aesthetics. Book your PRF consultation at Enclave Med Spa in San Elijo and let’s create a plan that restores your skin’s glow — naturally.
Introduction
Regenerative aesthetics has quickly become one of the most exciting frontiers in non-surgical facial rejuvenation. If you’ve heard about PRP (Platelet-Rich Plasma) or PRF (Platelet-Rich Fibrin), you’re not alone — both treatments use your body’s own healing factors to improve skin tone, texture, and volume. But which one is better?
At Enclave Med Spa in San Elijo, we specialize in advanced regenerative therapies that go beyond surface-level treatments. In this post, we break down the science, applications, and advantages of PRF vs. PRP — and why we choose PRF for our patients seeking natural, long-term results.
What Is PRP (Platelet-Rich Plasma)?
PRP has been used for over a decade in both medicine and aesthetics. It involves drawing a small amount of your blood, spinning it in a centrifuge to isolate platelet-rich plasma, and then injecting or microneedling it into the skin.
How PRP Works:
Delivers growth factors and platelets to accelerate healing
Often used in “vampire facials” or post-microneedling
Improves overall tone, texture, and healing response
Great for boosting collagen and healing after laser or RF
However, PRP uses an anticoagulant during processing to prevent clotting. This limits how long the growth factors remain active once reintroduced into the skin — they’re released all at once, then gone.
What Is PRF (Platelet-Rich Fibrin)?
PRF is the next-generation version of PRP — and it’s what we use at Enclave Med Spa. Like PRP, PRF is derived from your blood, but it’s spun at a slower speed and does not use anticoagulants.
This slower spin preserves more:
Platelets
Leukocytes (white blood cells)
Fibrin matrix
Stem cells
And most importantly, releases growth factors slowly over time
This means PRF stays active longer in your skin, allowing continued collagen production, improved skin quality, and gentle volume enhancement.
Key Differences Between PRP and PRF
Feature PRP PRF
Anticoagulant Used Yes No
Spin Speed High Low
Growth Factor Release Immediate Sustained (10–12 days)
Volume Restoration Minimal Moderate
Texture Improvement Good Excellent
Duration of Results Weeks Months
When Should You Choose PRF?
We recommend PRF for clients who want a natural, non-toxic, long-lasting rejuvenation strategy. PRF is ideal for:
Under-eye hollows and darkness
Fine lines around the mouth or eyes
Crepey skin texture
Loss of volume in cheeks, temples, or jawline
Patients who want natural results without dermal fillers
Clients seeking enhanced microneedling outcomes
How Many Treatments Are Needed?
Most clients benefit from a series of 2–3 PRF sessions, spaced about 4–6 weeks apart. Improvements continue gradually over the following 2–3 months as collagen rebuilds.
Why Enclave Med Spa in San Elijo Recommends PRF
We use only next-generation PRF, with custom protocols for injection and microneedling. Every treatment is personalized to your anatomy and skin needs. Our providers are clinically trained in regenerative aesthetics, and we combine PRF with modalities like Morpheus8, IPL, and chemical peels for amplified results.
Unlike clinics that still offer PRP out of habit, we choose PRF because it works better — and our patients see it in the mirror.
Internal Links
Learn more about Morpheus8 treatments
Explore our Membership Plans
Book a consultation
Ready to See the PRF Difference?
Experience next-level regenerative aesthetics. Book your PRF consultation at Enclave Med Spa in San Elijo and let’s create a plan that restores your skin’s glow — naturally.
Introduction
Regenerative aesthetics has quickly become one of the most exciting frontiers in non-surgical facial rejuvenation. If you’ve heard about PRP (Platelet-Rich Plasma) or PRF (Platelet-Rich Fibrin), you’re not alone — both treatments use your body’s own healing factors to improve skin tone, texture, and volume. But which one is better?
At Enclave Med Spa in San Elijo, we specialize in advanced regenerative therapies that go beyond surface-level treatments. In this post, we break down the science, applications, and advantages of PRF vs. PRP — and why we choose PRF for our patients seeking natural, long-term results.
What Is PRP (Platelet-Rich Plasma)?
PRP has been used for over a decade in both medicine and aesthetics. It involves drawing a small amount of your blood, spinning it in a centrifuge to isolate platelet-rich plasma, and then injecting or microneedling it into the skin.
How PRP Works:
Delivers growth factors and platelets to accelerate healing
Often used in “vampire facials” or post-microneedling
Improves overall tone, texture, and healing response
Great for boosting collagen and healing after laser or RF
However, PRP uses an anticoagulant during processing to prevent clotting. This limits how long the growth factors remain active once reintroduced into the skin — they’re released all at once, then gone.
What Is PRF (Platelet-Rich Fibrin)?
PRF is the next-generation version of PRP — and it’s what we use at Enclave Med Spa. Like PRP, PRF is derived from your blood, but it’s spun at a slower speed and does not use anticoagulants.
This slower spin preserves more:
Platelets
Leukocytes (white blood cells)
Fibrin matrix
Stem cells
And most importantly, releases growth factors slowly over time
This means PRF stays active longer in your skin, allowing continued collagen production, improved skin quality, and gentle volume enhancement.
Key Differences Between PRP and PRF
Feature PRP PRF
Anticoagulant Used Yes No
Spin Speed High Low
Growth Factor Release Immediate Sustained (10–12 days)
Volume Restoration Minimal Moderate
Texture Improvement Good Excellent
Duration of Results Weeks Months
When Should You Choose PRF?
We recommend PRF for clients who want a natural, non-toxic, long-lasting rejuvenation strategy. PRF is ideal for:
Under-eye hollows and darkness
Fine lines around the mouth or eyes
Crepey skin texture
Loss of volume in cheeks, temples, or jawline
Patients who want natural results without dermal fillers
Clients seeking enhanced microneedling outcomes
How Many Treatments Are Needed?
Most clients benefit from a series of 2–3 PRF sessions, spaced about 4–6 weeks apart. Improvements continue gradually over the following 2–3 months as collagen rebuilds.
Why Enclave Med Spa in San Elijo Recommends PRF
We use only next-generation PRF, with custom protocols for injection and microneedling. Every treatment is personalized to your anatomy and skin needs. Our providers are clinically trained in regenerative aesthetics, and we combine PRF with modalities like Morpheus8, IPL, and chemical peels for amplified results.
Unlike clinics that still offer PRP out of habit, we choose PRF because it works better — and our patients see it in the mirror.
Internal Links
Learn more about Morpheus8 treatments
Explore our Membership Plans
Book a consultation
Ready to See the PRF Difference?
Experience next-level regenerative aesthetics. Book your PRF consultation at Enclave Med Spa in San Elijo and let’s create a plan that restores your skin’s glow — naturally.
Introduction
Regenerative aesthetics has quickly become one of the most exciting frontiers in non-surgical facial rejuvenation. If you’ve heard about PRP (Platelet-Rich Plasma) or PRF (Platelet-Rich Fibrin), you’re not alone — both treatments use your body’s own healing factors to improve skin tone, texture, and volume. But which one is better?
At Enclave Med Spa in San Elijo, we specialize in advanced regenerative therapies that go beyond surface-level treatments. In this post, we break down the science, applications, and advantages of PRF vs. PRP — and why we choose PRF for our patients seeking natural, long-term results.
What Is PRP (Platelet-Rich Plasma)?
PRP has been used for over a decade in both medicine and aesthetics. It involves drawing a small amount of your blood, spinning it in a centrifuge to isolate platelet-rich plasma, and then injecting or microneedling it into the skin.
How PRP Works:
Delivers growth factors and platelets to accelerate healing
Often used in “vampire facials” or post-microneedling
Improves overall tone, texture, and healing response
Great for boosting collagen and healing after laser or RF
However, PRP uses an anticoagulant during processing to prevent clotting. This limits how long the growth factors remain active once reintroduced into the skin — they’re released all at once, then gone.
What Is PRF (Platelet-Rich Fibrin)?
PRF is the next-generation version of PRP — and it’s what we use at Enclave Med Spa. Like PRP, PRF is derived from your blood, but it’s spun at a slower speed and does not use anticoagulants.
This slower spin preserves more:
Platelets
Leukocytes (white blood cells)
Fibrin matrix
Stem cells
And most importantly, releases growth factors slowly over time
This means PRF stays active longer in your skin, allowing continued collagen production, improved skin quality, and gentle volume enhancement.
Key Differences Between PRP and PRF
Feature PRP PRF
Anticoagulant Used Yes No
Spin Speed High Low
Growth Factor Release Immediate Sustained (10–12 days)
Volume Restoration Minimal Moderate
Texture Improvement Good Excellent
Duration of Results Weeks Months
When Should You Choose PRF?
We recommend PRF for clients who want a natural, non-toxic, long-lasting rejuvenation strategy. PRF is ideal for:
Under-eye hollows and darkness
Fine lines around the mouth or eyes
Crepey skin texture
Loss of volume in cheeks, temples, or jawline
Patients who want natural results without dermal fillers
Clients seeking enhanced microneedling outcomes
How Many Treatments Are Needed?
Most clients benefit from a series of 2–3 PRF sessions, spaced about 4–6 weeks apart. Improvements continue gradually over the following 2–3 months as collagen rebuilds.
Why Enclave Med Spa in San Elijo Recommends PRF
We use only next-generation PRF, with custom protocols for injection and microneedling. Every treatment is personalized to your anatomy and skin needs. Our providers are clinically trained in regenerative aesthetics, and we combine PRF with modalities like Morpheus8, IPL, and chemical peels for amplified results.
Unlike clinics that still offer PRP out of habit, we choose PRF because it works better — and our patients see it in the mirror.
Internal Links
Learn more about Morpheus8 treatments
Explore our Membership Plans
Book a consultation
Ready to See the PRF Difference?
Experience next-level regenerative aesthetics. Book your PRF consultation at Enclave Med Spa in San Elijo and let’s create a plan that restores your skin’s glow — naturally.
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