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PRF vs. PRP: What’s Better for Skin Rejuvenation and Volume Loss?

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Our Team

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7/13/2025

Introduction

Regenerative aesthetics has quickly become one of the most exciting frontiers in non-surgical facial rejuvenation. If you’ve heard about PRP (Platelet-Rich Plasma) or PRF (Platelet-Rich Fibrin), you’re not alone — both treatments use your body’s own healing factors to improve skin tone, texture, and volume. But which one is better?


At Enclave Med Spa in San Elijo, we specialize in advanced regenerative therapies that go beyond surface-level treatments. In this post, we break down the science, applications, and advantages of PRF vs. PRP — and why we choose PRF for our patients seeking natural, long-term results.


What Is PRP (Platelet-Rich Plasma)?

PRP has been used for over a decade in both medicine and aesthetics. It involves drawing a small amount of your blood, spinning it in a centrifuge to isolate platelet-rich plasma, and then injecting or microneedling it into the skin.


How PRP Works:


Delivers growth factors and platelets to accelerate healing


Often used in “vampire facials” or post-microneedling


Improves overall tone, texture, and healing response


Great for boosting collagen and healing after laser or RF


However, PRP uses an anticoagulant during processing to prevent clotting. This limits how long the growth factors remain active once reintroduced into the skin — they’re released all at once, then gone.


What Is PRF (Platelet-Rich Fibrin)?

PRF is the next-generation version of PRP — and it’s what we use at Enclave Med Spa. Like PRP, PRF is derived from your blood, but it’s spun at a slower speed and does not use anticoagulants.


This slower spin preserves more:


Platelets


Leukocytes (white blood cells)


Fibrin matrix


Stem cells


And most importantly, releases growth factors slowly over time


This means PRF stays active longer in your skin, allowing continued collagen production, improved skin quality, and gentle volume enhancement.


Key Differences Between PRP and PRF

Feature PRP PRF

Anticoagulant Used Yes No

Spin Speed High Low

Growth Factor Release Immediate Sustained (10–12 days)

Volume Restoration Minimal Moderate

Texture Improvement Good Excellent

Duration of Results Weeks Months


When Should You Choose PRF?

We recommend PRF for clients who want a natural, non-toxic, long-lasting rejuvenation strategy. PRF is ideal for:


Under-eye hollows and darkness


Fine lines around the mouth or eyes


Crepey skin texture


Loss of volume in cheeks, temples, or jawline


Patients who want natural results without dermal fillers


Clients seeking enhanced microneedling outcomes


How Many Treatments Are Needed?

Most clients benefit from a series of 2–3 PRF sessions, spaced about 4–6 weeks apart. Improvements continue gradually over the following 2–3 months as collagen rebuilds.


Why Enclave Med Spa in San Elijo Recommends PRF

We use only next-generation PRF, with custom protocols for injection and microneedling. Every treatment is personalized to your anatomy and skin needs. Our providers are clinically trained in regenerative aesthetics, and we combine PRF with modalities like Morpheus8, IPL, and chemical peels for amplified results.


Unlike clinics that still offer PRP out of habit, we choose PRF because it works better — and our patients see it in the mirror.


Internal Links

Learn more about Morpheus8 treatments


Explore our Membership Plans


Book a consultation


Ready to See the PRF Difference?

Experience next-level regenerative aesthetics. Book your PRF consultation at Enclave Med Spa in San Elijo and let’s create a plan that restores your skin’s glow — naturally.



Introduction

Regenerative aesthetics has quickly become one of the most exciting frontiers in non-surgical facial rejuvenation. If you’ve heard about PRP (Platelet-Rich Plasma) or PRF (Platelet-Rich Fibrin), you’re not alone — both treatments use your body’s own healing factors to improve skin tone, texture, and volume. But which one is better?


At Enclave Med Spa in San Elijo, we specialize in advanced regenerative therapies that go beyond surface-level treatments. In this post, we break down the science, applications, and advantages of PRF vs. PRP — and why we choose PRF for our patients seeking natural, long-term results.


What Is PRP (Platelet-Rich Plasma)?

PRP has been used for over a decade in both medicine and aesthetics. It involves drawing a small amount of your blood, spinning it in a centrifuge to isolate platelet-rich plasma, and then injecting or microneedling it into the skin.


How PRP Works:


Delivers growth factors and platelets to accelerate healing


Often used in “vampire facials” or post-microneedling


Improves overall tone, texture, and healing response


Great for boosting collagen and healing after laser or RF


However, PRP uses an anticoagulant during processing to prevent clotting. This limits how long the growth factors remain active once reintroduced into the skin — they’re released all at once, then gone.


What Is PRF (Platelet-Rich Fibrin)?

PRF is the next-generation version of PRP — and it’s what we use at Enclave Med Spa. Like PRP, PRF is derived from your blood, but it’s spun at a slower speed and does not use anticoagulants.


This slower spin preserves more:


Platelets


Leukocytes (white blood cells)


Fibrin matrix


Stem cells


And most importantly, releases growth factors slowly over time


This means PRF stays active longer in your skin, allowing continued collagen production, improved skin quality, and gentle volume enhancement.


Key Differences Between PRP and PRF

Feature PRP PRF

Anticoagulant Used Yes No

Spin Speed High Low

Growth Factor Release Immediate Sustained (10–12 days)

Volume Restoration Minimal Moderate

Texture Improvement Good Excellent

Duration of Results Weeks Months


When Should You Choose PRF?

We recommend PRF for clients who want a natural, non-toxic, long-lasting rejuvenation strategy. PRF is ideal for:


Under-eye hollows and darkness


Fine lines around the mouth or eyes


Crepey skin texture


Loss of volume in cheeks, temples, or jawline


Patients who want natural results without dermal fillers


Clients seeking enhanced microneedling outcomes


How Many Treatments Are Needed?

Most clients benefit from a series of 2–3 PRF sessions, spaced about 4–6 weeks apart. Improvements continue gradually over the following 2–3 months as collagen rebuilds.


Why Enclave Med Spa in San Elijo Recommends PRF

We use only next-generation PRF, with custom protocols for injection and microneedling. Every treatment is personalized to your anatomy and skin needs. Our providers are clinically trained in regenerative aesthetics, and we combine PRF with modalities like Morpheus8, IPL, and chemical peels for amplified results.


Unlike clinics that still offer PRP out of habit, we choose PRF because it works better — and our patients see it in the mirror.


Internal Links

Learn more about Morpheus8 treatments


Explore our Membership Plans


Book a consultation


Ready to See the PRF Difference?

Experience next-level regenerative aesthetics. Book your PRF consultation at Enclave Med Spa in San Elijo and let’s create a plan that restores your skin’s glow — naturally.



Introduction

Regenerative aesthetics has quickly become one of the most exciting frontiers in non-surgical facial rejuvenation. If you’ve heard about PRP (Platelet-Rich Plasma) or PRF (Platelet-Rich Fibrin), you’re not alone — both treatments use your body’s own healing factors to improve skin tone, texture, and volume. But which one is better?


At Enclave Med Spa in San Elijo, we specialize in advanced regenerative therapies that go beyond surface-level treatments. In this post, we break down the science, applications, and advantages of PRF vs. PRP — and why we choose PRF for our patients seeking natural, long-term results.


What Is PRP (Platelet-Rich Plasma)?

PRP has been used for over a decade in both medicine and aesthetics. It involves drawing a small amount of your blood, spinning it in a centrifuge to isolate platelet-rich plasma, and then injecting or microneedling it into the skin.


How PRP Works:


Delivers growth factors and platelets to accelerate healing


Often used in “vampire facials” or post-microneedling


Improves overall tone, texture, and healing response


Great for boosting collagen and healing after laser or RF


However, PRP uses an anticoagulant during processing to prevent clotting. This limits how long the growth factors remain active once reintroduced into the skin — they’re released all at once, then gone.


What Is PRF (Platelet-Rich Fibrin)?

PRF is the next-generation version of PRP — and it’s what we use at Enclave Med Spa. Like PRP, PRF is derived from your blood, but it’s spun at a slower speed and does not use anticoagulants.


This slower spin preserves more:


Platelets


Leukocytes (white blood cells)


Fibrin matrix


Stem cells


And most importantly, releases growth factors slowly over time


This means PRF stays active longer in your skin, allowing continued collagen production, improved skin quality, and gentle volume enhancement.


Key Differences Between PRP and PRF

Feature PRP PRF

Anticoagulant Used Yes No

Spin Speed High Low

Growth Factor Release Immediate Sustained (10–12 days)

Volume Restoration Minimal Moderate

Texture Improvement Good Excellent

Duration of Results Weeks Months


When Should You Choose PRF?

We recommend PRF for clients who want a natural, non-toxic, long-lasting rejuvenation strategy. PRF is ideal for:


Under-eye hollows and darkness


Fine lines around the mouth or eyes


Crepey skin texture


Loss of volume in cheeks, temples, or jawline


Patients who want natural results without dermal fillers


Clients seeking enhanced microneedling outcomes


How Many Treatments Are Needed?

Most clients benefit from a series of 2–3 PRF sessions, spaced about 4–6 weeks apart. Improvements continue gradually over the following 2–3 months as collagen rebuilds.


Why Enclave Med Spa in San Elijo Recommends PRF

We use only next-generation PRF, with custom protocols for injection and microneedling. Every treatment is personalized to your anatomy and skin needs. Our providers are clinically trained in regenerative aesthetics, and we combine PRF with modalities like Morpheus8, IPL, and chemical peels for amplified results.


Unlike clinics that still offer PRP out of habit, we choose PRF because it works better — and our patients see it in the mirror.


Internal Links

Learn more about Morpheus8 treatments


Explore our Membership Plans


Book a consultation


Ready to See the PRF Difference?

Experience next-level regenerative aesthetics. Book your PRF consultation at Enclave Med Spa in San Elijo and let’s create a plan that restores your skin’s glow — naturally.



Introduction

Regenerative aesthetics has quickly become one of the most exciting frontiers in non-surgical facial rejuvenation. If you’ve heard about PRP (Platelet-Rich Plasma) or PRF (Platelet-Rich Fibrin), you’re not alone — both treatments use your body’s own healing factors to improve skin tone, texture, and volume. But which one is better?


At Enclave Med Spa in San Elijo, we specialize in advanced regenerative therapies that go beyond surface-level treatments. In this post, we break down the science, applications, and advantages of PRF vs. PRP — and why we choose PRF for our patients seeking natural, long-term results.


What Is PRP (Platelet-Rich Plasma)?

PRP has been used for over a decade in both medicine and aesthetics. It involves drawing a small amount of your blood, spinning it in a centrifuge to isolate platelet-rich plasma, and then injecting or microneedling it into the skin.


How PRP Works:


Delivers growth factors and platelets to accelerate healing


Often used in “vampire facials” or post-microneedling


Improves overall tone, texture, and healing response


Great for boosting collagen and healing after laser or RF


However, PRP uses an anticoagulant during processing to prevent clotting. This limits how long the growth factors remain active once reintroduced into the skin — they’re released all at once, then gone.


What Is PRF (Platelet-Rich Fibrin)?

PRF is the next-generation version of PRP — and it’s what we use at Enclave Med Spa. Like PRP, PRF is derived from your blood, but it’s spun at a slower speed and does not use anticoagulants.


This slower spin preserves more:


Platelets


Leukocytes (white blood cells)


Fibrin matrix


Stem cells


And most importantly, releases growth factors slowly over time


This means PRF stays active longer in your skin, allowing continued collagen production, improved skin quality, and gentle volume enhancement.


Key Differences Between PRP and PRF

Feature PRP PRF

Anticoagulant Used Yes No

Spin Speed High Low

Growth Factor Release Immediate Sustained (10–12 days)

Volume Restoration Minimal Moderate

Texture Improvement Good Excellent

Duration of Results Weeks Months


When Should You Choose PRF?

We recommend PRF for clients who want a natural, non-toxic, long-lasting rejuvenation strategy. PRF is ideal for:


Under-eye hollows and darkness


Fine lines around the mouth or eyes


Crepey skin texture


Loss of volume in cheeks, temples, or jawline


Patients who want natural results without dermal fillers


Clients seeking enhanced microneedling outcomes


How Many Treatments Are Needed?

Most clients benefit from a series of 2–3 PRF sessions, spaced about 4–6 weeks apart. Improvements continue gradually over the following 2–3 months as collagen rebuilds.


Why Enclave Med Spa in San Elijo Recommends PRF

We use only next-generation PRF, with custom protocols for injection and microneedling. Every treatment is personalized to your anatomy and skin needs. Our providers are clinically trained in regenerative aesthetics, and we combine PRF with modalities like Morpheus8, IPL, and chemical peels for amplified results.


Unlike clinics that still offer PRP out of habit, we choose PRF because it works better — and our patients see it in the mirror.


Internal Links

Learn more about Morpheus8 treatments


Explore our Membership Plans


Book a consultation


Ready to See the PRF Difference?

Experience next-level regenerative aesthetics. Book your PRF consultation at Enclave Med Spa in San Elijo and let’s create a plan that restores your skin’s glow — naturally.



Great vibe. Experienced staff, excellent results. Highly recommend. Support this awesome business!

L.M. Google

I just had my first treatment at Enclave and had the best experience! The spa is clean and beautiful and the entire staff is friendly and welcoming. Meri is an excellent injector! She is very knowledgeable and talked me through my filler and Dysport process, the level of care I experienced is top notch. She made me feel at ease and made the injections very comfortable. My results look natural, exactly what I wanted. I look forward to returning for more treatments!

K.M. Google

Great friendly, staff, very convenient! They got me in on short notice.

M.B. Google

Love the girls at Enclave, I see Meri for my injectables & laser hair removal, and she absolutely is a pro at what she does. Quick and painless. I would absolutely recommend Enclave to everyone!

T.T. Google

Great experience here. Will for sure be coming back!

J.J. Google

33

Total Reviews

5

Average Rating

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* All information subject to change. Images may contain models. Individual results are not guaranteed and may vary.